CRISPR-related publications


Chew WL, Tabebordbar M, Cheng JK, Mali P, Wu EY, Ng AH, Zhu K, Wagers AJ, Church GM (2016). A multifunctional AAV-CRISPR-Cas9 and its host response. Nature Methods 13(10):868-74. PMID: 27595405

Vasiliou SK, Diamandis EP, Church GM, Greely HT, Baylis F, Thompson C, Schmitt-Ulms G (2016). CRISPR-Cas9 System: Opportunities and Concerns. Clinical Chemistry 62(10):1304-11. PMID: 27551006

Shipman SL, Nivala J, Macklis JD, Church GM (2016). Molecular recordings by directed CRISPR spacer acquisition. Science 353(6298):aaf1175. PMID: 27284167

Boeke JD, Church G, Hessel A, Kelley NJ, Arkin A, Cai Y, Carlson R, Chakravarti A, Cornish VW, Holt L, Isaacs FJ, Kuiken T, Lajoie M, Lessor T, Lunshof J, Maurano MT, Mitchell LA, Rine J, Rosser S, Sanjana NE, Silver PA, Valle D, Wang H, Way JC, Yang L (2016). GENOME ENGINEERING. The Genome Project-Write. Science 353(6295):126-7. PMID: 27256881

Vora S, Tuttle M, Cheng J, Church G (2016). Next stop for the CRISPR revolution: RNA-guided epigenetic regulators. The FEBS Journal 283(17):3181-93. PMID: 27248712

Chavez A, Tuttle M, Pruitt BW, Ewen-Campen B, Chari R, Ter-Ovanesyan D, Haque SJ, Cecchi RJ, Kowal EJ, Buchthal J, Housden BE, Perrimon N, Collins JJ, Church G (2016). Comparison of Cas9 activators in multiple species. Nature Methods 13(7):563-7. PMID: 27214048

Braff JL, Yaung SJ, Esvelt KM, Church GM (2016). Characterization of Cas9-Guide RNA Orthologs. Cold Spring Harbor Protocols (5):pdb.top086793. PMID: 27140923

Braff JL, Yaung SJ, Esvelt KM, Church GM (2016). Characterizing Cas9 Protospacer-Adjacent Motifs with High-Throughput Sequencing of Library Depletion Experiments. Cold Spring Harbor Protocols (5):pdb.prot090183. PMID: 27140916

Tabebordbar M, Zhu K, Cheng JK, Chew WL, Widrick JJ, Yan WX, Maesner C, Wu EY, Xiao R, Ran FA, Cong L, Zhang F, Vandenberghe LH, Church GM, Wagers AJ (2016). In vivo gene editing in dystrophic mouse muscle and muscle stem cells. Science. 351(6271):407-11. PMID: 26721686

Feng J, Jester BW, Tinberg CE, Mandell DJ, Antunes MS, Chari R, Morey KJ, Rios X, Medford JI, Church GM, Fields S, Baker D (2015). A general strategy to construct small molecule biosensors in eukaryotes. eLife. pii: e10606. PMID: 26714111

DiCarlo JE, Chavez A, Dietz SL, Esvelt KM, Church GM (2015). Safeguarding CRISPR-Cas9 gene drives in yeast. Nature Biotechnology. 33(12):1250-1255. PMID: 26571100

Yang L, Güell M, Niu D, George H, Lesha E, Grishin D, Aach J, Shrock E, Xu W, Poci J, Cortazio R, Wilkinson RA, Fishman JA, Church G (2015). Genome-wide inactivation of porcine endogenous retroviruses (PERVs). Science. 350(6264):1101-4. PMID: 26456528

Kiani S, Chavez A, Tuttle M, Hall RN, Chari R, Ter-Ovanesyan D, Qian J, Pruitt BW, Beal J, Vora S, Buchthal J, Kowal EJ, Ebrahimkhani MR, Collins JJ, Weiss R, Church G (2015). Cas9 gRNA engineering for genome editing, activation and repression. Nature Methods. 12(11):1051-4. PMID: 26344044

Akbari OS, Bellen HJ, Bier E, Bullock SL, Burt A, Church GM, Cook KR, Duchek P, Edwards OR, Esvelt KM, Gantz VM, Golic KG, Gratz SJ, Harrison MM, Hayes KR, James AA, Kaufman TC, Knoblich J, Malik HS, Matthews KA, O'Connor-Giles KM, Parks AL, Perrimon N, Port F, Russell S, Ueda R, Wildonger J (2015). BIOSAFETY. Safeguarding gene drive experiments in the laboratory. Science. 349(6251):927-9. PMID: 26229113

Chari R, Mali P, Moosburner M, Church GM (2015). Unraveling CRISPR-Cas9 genome engineering parameters via a library-on-library approach. Nature Methods. 12(9):823-826. PMID: 26167643

Chavez A, Scheiman J, Vora S, Pruitt BW, Tuttle M, P R Iyer E, Lin S, Kiani S, Guzman CD, Wiegand DJ, Ter-Ovanesyan D, Braff JL, Davidsohn N, Housden BE, Perrimon N, Weiss R, Aach J, Collins JJ, Church GM (2015). Highly efficient Cas9-mediated transcriptional programming. Nature Methods. 12(4):326-8. PMID: 25730490

Yang L, Grishin D, Wang G, Aach J, Zhang CZ, Chari R, Homsy J, Cai X, Zhao Y, Fan JB, Seidman C, Seidman J, Pu W, Church G (2014). Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells. Nature Communications. PMID: 25425480

Byrne SM, Ortiz L, Mali P, Aach J, Church GM (2014). Multi-kilobase homozygous targeted gene replacement in human induced pluripotent stem cells. Nucleic Acids Research. 43(3):e21. PMID: 25414332

Byrne SM, Mali P, Church GM (2014). Genome editing in human stem cells. Methods in Enzymology. 546:119-38. PMID: 25398338

Esvelt KM, Smidler AL, Catteruccia F, Church GM (2014). Concerning RNA-guided gene drives for the alteration of wild populations. eLife. PMID: 25035423

Yang L, Yang JL, Byrne S, Pan J, Church GM (2014). CRISPR/Cas9-Directed Genome Editing of Cultured Cells. Current Protocols in Molecular Biology. 107:31.1.1-31.1.17. PMID: 24984853

Aach J, Mali P, Church GM (2014). CasFinder: Flexible algorithm for identifying specific Cas9 targets in genomes. BioRxiv. Link

Yaung SJ, Esvelt KM, Church GM (2014). CRISPR/Cas9-mediated phage resistance is not impeded by the DNA modifications of phage T4. PLoS One. PMID: 24886988

Montague TG, Cruz JM, Gagnon JA, Church GM, Valen E (2014). CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing. Nucleic Acids Research. PMID: 24861617

Yang L, Mali P, Kim-Kiselak C, Church G (2014). CRISPR-Cas-mediated targeted genome editing in human cells. Methods in Molecular Biology. 1114:245-67. PMID: 24557908

Mali P, Esvelt KM, Church GM (2013). Cas9 as a versatile tool for engineering biology. Nature Methods. 10(10):957-63. PMID: 24076990

Esvelt KM, Mali P, Braff JL, Moosburner M, Yaung SJ, Church GM (2013). Orthogonal Cas9 proteins for RNA-guided gene regulation and editing. Nature Methods. 10(11):1116-21. PMID: 24076762

Tzur YB, Friedland AE, Nadarajan S, Church GM, Calarco JA, Colaiácovo MP (2013). Heritable custom genomic modifications in Caenorhabditis elegans via a CRISPR-Cas9 system. Genetics. 195(3):1181-5. PMID: 23979579

Li JF, Norville JE, Aach J, McCormack M, Zhang D, Bush J, Church GM, Sheen J (2013). Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9. Nature Biotechnology. 31(8):688-91. PMID: 23929339

Yang L, Guell M, Byrne S, Yang JL, De Los Angeles A, Mali P, Aach J, Kim-Kiselak C, Briggs AW, Rios X, Huang PY, Daley G, Church G (2013). Optimization of scarless human stem cell genome editing. Nucleic Acids Research. 41(19):9049-61. PMID: 23907390

Mali P, Aach J, Stranges PB, Esvelt KM, Moosburner M, Kosuri S, Yang L, Church GM (2013). CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering. Nature Biotechnology. 31(9):833-8. PMID: 23907171

Friedland AE, Tzur YB, Esvelt KM, Colaiácovo MP, Church GM, Calarco JA (2013). Heritable genome editing in C. elegans via a CRISPR-Cas9 system. Nature Methods. 10(8):741-3. PMID: 23817069

DiCarlo JE, Norville JE, Mali P, Rios X, Aach J, Church GM (2013). Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems. Nucleic Acids Research. 41(7):4336-43. PMID: 23460208

Mali P, Yang L, Esvelt KM, Aach J, Guell M, DiCarlo JE, Norville JE, Church GM (2013). RNA-guided human genome engineering via Cas9. Science. 339(6121):823-6. PMID: 23287722


Any suggestions or comments can be e-mailed to sgRNAScorer 'at' hms 'dot' harvard 'dot' edu

Updated October 1st, 2016